Centers of Excellence
One Vision, Seven Forces
Where Excellence Takes Shape
Seven Centers of Excellence. One shared mission to engineer what’s next.
Explore the pillars that drive innovation, set standards, and lead transformation across our technology landscape.
Bio-INvENT
Center of Excellence
Ideation, design, development, testing and commercialization of innovative biomedical products — at the interface of biology, engineering and nanotechnology.
Vision & Mission
Our Vision
To become a world-class Center of Excellence in biomedical research, innovation and entrepreneurship.
Our Mission
- Establish a state-of-the-art biomedical research infrastructure
- Train and create future leaders in biomedical research and innovation
- Provide affordable and high-efficiency biomedical products to the healthcare sector
Bio-INvENT CoE works at the interface of biology, medicine, chemical engineering, materials, nanotechnology and physics — conducting cutting-edge basic research in cancer biology, stem cell biology and ocular diseases, leading to the identification of unmet needs and development of engineering-driven biomedical solutions.
Focus Areas
01
Cancer Stem Cell Biology, Immunology & Immunotherapy
02
3D Bioprinting for Model Development — Cancer, Cornea & Skin
03
Cell-based Active Targeted Drug Delivery
04
Redox Biology & Nanomedicine
05
Corneal Pathophysiology & Pharmacology
06
AI-based Corneal Image Processing to Predict Treatment Outcomes
07
Nanomedicine to Tackle Corneal Storage & Transplant Rejection
08
Stimuli-responsive Drug Delivery to Treat Uveitis of the Eye
09
Ocular Surface Microenvironment Biosensing
10
Nongenetic Engineering of Mesenchymal Stem Cell
11
Plasma Activated Water-mediated Cancer Therapy
12
Nanoliposomes for Delivery of Nanomedicine & Therapeutics
13
COMSOL-based Simulation of Cell Lysis in Microfluidic Devices
14
Microfluidic Device for Generating Cell-based Nanovesicles
15
Microfluidic Device for Generating Liposome-coated Nanoparticles
Research Funding
₹5+ Crores
Total Research Funding Secured
Department of Biotechnology, Govt. of India
2023 – 2027
₹ 3.36 Cr
Sree Siddaganga Education Society, Tumkur
2017 – 2025
₹ 95 L
DST–SERB, Govt. of India
2018 – 2021
₹ 35 L
Cutis Academy of Cutaneous Sciences
2026 – 2027
₹ 34 L
Board of Research for Nuclear Sciences, Govt. of India
2018 – 2021
₹ 29 L
Vision Group on Science & Technology, Govt. of Karnataka
2020 – 2022
₹ 25 L
Association for Research in Vision Science & Ophthalmology, USA
2022
₹ 7.5 L
SigmaXi & National Academy of Sciences, USA
2024 – 2025
₹ 5.22 L
DST-Lockheed Martin-Tata Trusts
2019
₹ 10 L
Cutis Medi Apparels LLP
2026 – 2027
₹ 9 L
Indo-French Centre for Promotion of Advanced Research
2016
₹ 2 L
Global Collaboraters
Prof. S P Srinivas
Indiana University School of Optometry, Bloomington, IN, USA
Prof. Joseph Bonanno
Indiana University School of Optometry, Bloomington, IN, USA
Dr. Nitin Joshi
Harvard Medical School, Boston MA, USA
Dr. Jeffrey Karp
Harvard-MIT Health Sciences Technology Division, Cambridge, MA, USA
Dr. Arghya Paul
University of Western Ontario, Ontario, Canada
Dr. Chi-Hwa Wang
National University of Singapore, Singapore
Prof. William B Krantz
University of Colorado, Boulder
Dr. Mohan Verma
IIT Delhi
Dr. Suhanya Duraiswamy
IIT Hyderabad
Dr. Raju K Gupta
IIT Kanpur
Dr. Dharitri Rath
IIT Jammu
Dr. Abhijit Majumder
IIT Bombay
Dr. Lakshminarayana Rao
Indian Institute of Science (IISc), Bangalore
Dr. Santosh K Sandur
Bhabha Atomic Research Center (BARC), Mumbai
Dr. Nandakumar D N
NIMHANS, Bengaluru
Dr. Prema Padmanabhan
Sankara Nethralaya, Chennai
Dr. B S Chandrashekhar
Cutis Hospital, Bengaluru
Equipment & Instruments
E-01
Vertical Autoclave
Aspire Inc
E-02
Analytical Microbalance
Shimadzu
E-03
Automatic Ice Flaker
Labman Scientific
E-04
−20°C Freezer
Celfrost, USA
E-05
−80°C Freezer
PHCBI, Panasonic
E-06
Biosafety Cabinet Class II
Kewaunee, Japan
E-07
CO₂ Incubator
PHCBI, Panasonic
E-08
3D Bioprinter
Alfatek Systems (Anga Pro)
E-09
Chemidoc Imaging System
UVITech, UK
E-10
Microplate Reader
Thermo Scientific, USA
E-11
Inverted Fluorescence Microscope
Zeiss Axiovert 5, Germany
E-12
Laboratory Refrigerator
Celfrost, USA
E-13
pH Meter
EUTECH
E-14
Centrifuge
Eppendorf
E-15
Centrifuge
Remi Inc
E-16
Ultrasonic Waterbath
Labman Scientific
E-17
Vortex Mixer
GeNei
E-18
Cold Room
Bluecold
E-19
Optical Microscope
Labomed
E-20
Quantitative PCR
HiMedia
E-21
Hot Air Oven
Aspire Inc
E-22
Liquid Nitrogen Container
Thermo Scientific
Research Facilities
Class II Mammalian Cell Culture Facility
High Resolution Bioimaging Facility (Zeiss Axiovert 5)
Protein / DNA / RNA Quantification Facility (UVITech ChemiDoc)
Quantitative PCR Facility (HiMedia)
Biochemical Assay Facility (Microplate Reader)
Cell & Molecular Biology Facility — DNA/RNA & Protein Isolation
3D Bioprinting Facility (Alfatek Anga Pro Bioprinter)
Optical Microscope for Cell Visualization (LaboMed)
Freezer Facility — Liquid N₂ −80°C and −20°C
Nanobioengineering Facility — Probe Sonicator, Rotary Vacuum Evaporator
Industry Consultancy
Cutis Academy of Cutaneous Sciences
Protocol development for melanocyte isolation and purification for autologous transplantation in vitiligo patients.
Cutis Medi Apparels LLP
Fabrics functionalized with Carbon Quantum Dot–stabilized nanoparticles for advanced textile applications.
Ongoing & Completed Projects
01
Development, Optimization, and Antifungal Evaluation of Fabrics Functionalized with Carbon Quantum Dot–stabilized Nanoparticles for Textile Applications
02
Development and standardization of protocols for isolation, culture, characterization and purification of autologous melanocytes for transplantation in Indian vitiligo patients
03
Optimization and cost analysis of silver nanoparticles synthesis process for antimicrobial textile application
04
Investigation of the protective effects of AMPK activation against energy stress in cold-stored ex vivo donor corneal endothelium
05
Network center for research on glioblastoma stem cell-targeted T-Cell immunotherapy using non-genetically engineered mesenchymal stromal cells
06
Investigation of ferroptosis as the mechanism of hypothermia-induced cell death and barrier dysfunction in cold stored ex vivo corneal endothelium
07
Rescuing the hypothermia- and cytokine-induced damage to donor corneal endothelial functions by pre-treatment with microtubule stabilizers
08
Unraveling a new strategy of inhibition of Cholesteryl ester transfer protein by small molecule inhibitors through site directed mutagenesis and molecular dynamics simulation studies
09
CLeONs: High efficiency contact lens-coated oxygen nanosensors for eye clinics
10
Nanoparticle-based prophylactic drug delivery to the corneal endothelium
Faculty In-charge
Dr. Sudhir H Ranganath
Associate Professor & Founder — Bio-INvENT CoE
Department of Chemical Engineering
Siddaganga Institute of Technology, Tumakuru, Karnataka
Gallery
